Comprised of faculty that span pharmaceutical and pharmacological research, the Department of Pharmaceutical Sciences is in the process of expanding and strengthening its research portfolio.
Existing areas of expertise include drug delivery, drug discovery, epigenetics, bioanalytical technologies, cell signaling, pharmacokinetics, pharmacodynamics, and neuroscience (view the below list of recent scholarly activity for additional insights into the research being conducted by members of the Department).
The Department supports both the bachelor’s and master’s degree programs in Pharmaceutical Sciences in addition to teaching courses in the Doctor of Pharmacy program.
Departmental faculty are centralized in the Biosciences Research Building (BRB).
Scholarly Activity Reports
2020 scholarly activity report
The activities listed below are by members of the Department of Pharmaceutical Sciences on the Albany Campus and span the period from January 1, 2020 - December 31, 2020.
* ACPHS faculty denoted in bold.
Awards
Christopher L. Cioffi 2020 Albany College of Pharmacy and Health Sciences Researcher of the Year Award.
Presentations & Conferences
Regional
K. Jin, Crosstalk between stromal components and breast cancer via secreted factors enhances tumor growth and metastasis, Nanobioseminar, Colleges of Nanoscale Science & Engineering SUNY Polytechnic Institute. Albany NY, April 1, 2020.
K. Jin, Crosstalk between stromal components and endocrine resistant breast cancer via secreted factors enhances tumor growth and metastasis, ACPHS Annual Research Forum, Albany NY, April 17, 2020.
M. Musteata and Galke D.: “Measurement of Free Concentrations of Testosterone Using Newly Developed SpinTip Microextraction Devices with Polyacrylonitrile” presentation at 68th ASMS Conference, Houston, TX, June 2020 (changed to online format).
M. Musteata and Galke D.: “Development of Biocompatible SpinTip Microextraction Devices with Polyacrylonitrile” presentation at 10th Annual Research Symposium, ACPHS, Albany, NY, April 2020.
Abstracts
Sumit Kamat*, Sonia Parikh and Manish B. Shah. Crystal Structure of CYP2C9*8 Genetic Variant Bound to an Anti-Hypertensive Drug Losartan. Experimental Biology 2020, San Diego, CA. (*Selected for Daily Datablitz talk and received graduate student travel award from the American Society of Pharmacology for Experimental Therapeutics (ASPET) to attend the meeting. Conference canceled due COVID-19.
Dylan Davie*, Sonia Parikh and Manish B. Shah. Insights into the Effect of Genetic Variation in CYP2C9 (*11) on Drug Binding. Experimental Biology 2020, San Diego, CA. Meeting cancelled due to COVID-19 pandemic. *Received undergraduate student travel stipend from the Albany College of Pharmacy and Health Sciences, and the Department of Pharmaceutical Sciences to attend the meeting. Conference canceled due COVID-19
Invited
C. Cioffi, Photoswitchable ORG25543 congener enables optical control of glycine transporter. 30th Annual ACPHS Research Symposium, Albany College of Pharmacy and Health Sciences, Albany, New York, US, April 17, 2020.
M. Shah, Annual Research Symposium Podium Session – “Functional and Structural Basis of Genetic Polymorphisms in Human Cytochrome P450 2C9: Insights into the Effect of *2 Variant”, April 17, ACPHS, Albany, NY.
Posters
K. Jin, Adipsin promotes tumor progression in ESR1 mutant breast cancer cells. AACR Virtual Annual Meeting II, June 22-24, 2020.
Nast N and K. Jin. Identification and validation of secreted factors in the crosstalk between HOXB7 overexpressing cells and stromal cells. ACPHS Annual Research Forum, Albany NY, April 16, 2020.
Pandithar S and K. Jin. Crosstalk between stromal components and endocrine resistant breast cancer via secreted factors enhances tumor growth and metastasis. ACPHS Annual Research Forum, Albany NY, April 16, 2020.
Malone MK and K. Jin. Adipsin promotes tumor progression in ESR1 mutant ER+ breast cancer cells. ACPHS Annual Research Forum, Albany NY, April 16, 2020.
Outside Services
Editorial and Journal Reviewing Experience
Christopher L. Cioffi, "Journal of Medicinal Chemistry", Reviewer, 2010-Present
Christopher L. Cioffi, "Journal of Organic Chemistry", Reviewer, 2010-Present
Christopher L. Cioffi, "Medicinal Chemistry Letters", Reviewer, 2010-Present
Christopher L. Cioffi, "Bioorganic and Medicinal Chemistry Letters", Reviewer, 2010-Present
Christopher L. Cioffi, "Current Pharmaceutical Design", Reviewer, 2010-Present
Christopher L. Cioffi, "Journal of Pharmacology and Experimental Therapeutics", Reviewer, 2019-Present
Christopher L. Cioffi, "Neuroscience and Behavioral Reviews", Reviewer, 2021
Christopher L. Cioffi, " Biomolecules", Reviewer, 2021
Christopher L. Cioffi, "Frontiers in Molecular Neuroscience"; working on the launch of a new section: “Pain Mechanisms and Modulators”, Associate Editor, 2021.
Christopher L. Cioffi, "Topics in Medicinal Chemistry"; serving as an editor and chapter contributor for a new volume in Topics in Medicinal Chemistry focused on Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases. Volume Editor. 2018-2020.
Manish B. Shah, NIH MSFA Study Section (Macromolecular Structure and Function A) - 02/2020. Participated in person.
Manish B. Shah, Invited to review a manuscript for the Journal of Chemical Information and Modeling - ACS publications and Drug Metabolism and Disposition – ASPET publications.
Review Boards and Committees
Christopher L. Cioffi National Institutes of Health, review panel to evaluate U18 Research Demonstration – Cooperative Agreement applications; Step Up for Substance Use Disorders (SUD); NIH/NIDA Study Section ZDA1 SKM-D (6), June, 2020. Ad Hoc Member
Christopher L. Cioffi National Institutes of Health, small business panel on Drug Discovery for Aging, Neuropsychiatric and Neurologic Disorders; NIH ZRG1 ETTN-H (11), November, 2020 – Present. Member.
Manish B. Shah, Elected as Councilor to ASPET - Member of the executive committee (July 2020 to June 2023) – Drug metabolism and disposition division.
Manish B. Shah, Nominated for Secretary/Treasurer for ASPET – Drug metabolism and disposition division.
Manish B. Shah, Invited as judge for the student and postdoc poster award competition at The 40th Midwest Enzyme Chemistry Conference, October 2020 – Virtual from the University of Texas at Arlington.
Manish B. Shah, Student Summer Research Award to an undergraduate BSPS student Thomas Yarbrough in the laboratory studying genetic polymorphisms in CYP2C9.
M. MUSTEATA, Associate Editor for the journal “Bioanalysis”.
Publications
National
M. MUSTEATA, Cibotaru D., Celestin M.N., Kane M., and Musteata F.M.: “Simultaneous Determination of Free Concentration, Total Concentration, and Plasma Binding Capacity,” Journal of Pharmaceutical Sciences, 110(3), p. 1401–1411, http://doi.org/10.1016/j.xphs.2020.12.001, 2020.
M. MUSTEATA, LaPorte B. and Musteata F.M.: “Increasing the Accuracy of Total Body Clearance Measurement,” Journal of Pharmaceutical Sciences, 109(6), p. 2079-2089, http://doi.org/10.1016/j.xphs.2020.03.002, 2020.
HAIAN ZHENG, Shargel and Yu’s Applied Biopharmaceutics and Pharmacokinetics, 8th Edition, Chapter 14 Intravenous Infusion, Edited by Murray P Ducharme and Leon Shargel, McGraw-Hill, 2020.
Books
C. L. Cioffi, (2020) Volume Editor: Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases: chapter author; Introduction: Overview of the Human Eye, Mammalian Retina, and the Retinoid Visual Cycle. In: Topics in Medicinal Chemistry. Springer, Berlin, Heidelberg; ISBN 978-3-030-56618-0.
Peer Review
C. L. Cioffi, Muthuraman, P.; Raja, A.; Varadi, A.; Racz, B.; Petrukhin, K. Discovery of bispecific antagonists of retinol binding protein 4 that stabilize transthyretin tetramers: scaffolding hopping, optimization, and preclinical pharmacological evaluation as a potential therapy for two common age-related comorbidities. J. Med. Chem. 2020, 63, 11054-11084; PMID: 32878437.
Mostyn, S. N.; Sarker, S.; Muthuraman, P.; Raja, A.; Shimmon, S.; Rawling, T.; Cioffi, C. L.; Vandenberg, R. J. Photoswitchable ORG25543 congener enables optical control of glycine transporter 2. ACS Chem. Neurosci. 2020, 11, 1250-1258; PMID: 32191428.
Recommended in Faculty Opinions (F1000): Lowe J: Faculty Opinions Recommendation of [Cioffi CL et al., J. Med. Chem. 2020, 63, 11054-11084]. In Faculty Opinions, September 20, 2020.
Malone MS, Smrekar K, Park S, Blakely B, Walter A, Nasta N, Park J, Considine M, Danilova L, Pandey N, Fertig E, Popel A, and Jin K*. Cytokines secreted by stromal cells in TNBC microenvironment as potential targets for cancer therapy: experimental and bioinformatics predictions. Cancer Biol Ther. 2020 Jun 2;21(6):560-569.
K. Jin, Peer reviewer for Cancer Research, Frontier Oncology, Drug Design, Development and Therapy, JECC, Cancer Medicine.
Sonia Parikh, Chiara Evans, Juliet Obi, Qinghai Zhang, Keiko Maekawa, Karen Glass, and Manish B. Shah*. Structure of Cytochrome P450 2C9*2 in Complex with Losartan: Insights into the Effect of Genetic Polymorphism. Molecular Pharmacology. 2020. 98: 529-539. (Article figure selected for the Cover illustration of the November 2020 issue) (*Corresponding author)
Grants
Christopher L. Cioffi Title: Pharmacological Treatment for Atrophic Age-Related Macular Degeneration Compounded by Common Forms of Age-Related Amyloid Disease Number: R01EY028549-01; NIH/NEI. Collaborators: Konstantin Petrukhin, Ph.D., Columbia University, New York, NY. Total Funds: $1,487,698. Dates of Funding Period: 02/01/2018 – 01/31/2021 (no-cost extension: end date 01/31/2022). Role: Principal Investigator (MPI).
Christopher L. Cioffi Title: Discovery and Development of Novel Glycine Transporter-2 Inhibitors for the Treatment of Neuropathic Pain. Number: 1R01DA048879-01; NIH/NIDA Collaborators: Robert Vandenberg, Ph.D., University of Sydney, Australia . Total Funds: $1,832,790. Dates of Funding: 09/30/2019 – 06/30/2023. Role: Contact Principal Investigator.
Kideok Jin, Title: The role of secreted factors in crosstalk between endocrine resistant breast cancer and stroma. Grantor: 2020-2021 ACPHS Scholarship of Discovery Grant. Total Funds: $5,000. Dates: 5/25/2021 – 6/30/2021. Role: Principal Investigator.
Manish B. Shah, Title: Genetic and Structural Determinants of Warfarin and Losartan Binding to Cytochrome P450 2C9. Grantor: American Heart Association, Institutional Research Enhancement Award. 19AIREA34450040. Funding Amount: $154,000. Date: 07/01/2019 – 06/30/2021. Role: Principal Investigator
- Subramaniam R, Lynch S, Cen Y, Balaz S. Polarity of Hydrated Phosphatidylcholine Headgroups. Langmuir (under review).
Yana Cen
- Wood M, Rymarchyk S, Zheng S, Cen Y. Trichostatin A inhibits deacetylation of histone H3 and p53 by SIRT6. Archives of Biochemistry and Biophysics, 2018, 638, 8-17.
- Graham E, Rymarchyk S, Wood M, Cen Y. Development of Activity-Based Chemical Probes for Human Sirtuins. ACS Chemical Biology, 2018, 13, 782-792.
- Tran A, Yokose R, Cen Y. Chemo-enzymatic Synthesis of Isotopically Labeled Nicotinamide Riboside. Organic and Biomolecular Chemistry, 2018, 16, 3662-3671.
- Szymanski M, Cen Y, Yin W. AP Lyase Activity of EXOG Suggests a Unified Mechanism for Mitochondrial DNA Base Excision Repair. Nature Structural & Molecular Biology (under review).
- Subramaniam R, Lynch S, Cen Y, B alaz S. Polarity of Hydrated Phosphatidylcholine Headgroups. Langmuir (submitted).
Karen C. Glass
- Gay JC, Eckenroth BE, Evans CE, Langini C, Carlson C, Lloyd JT, Caflisch A, Glass KC. (2018) Disulfide bridge formation influences ligand recognition by the ATAD2 bromodomain. Proteins: Structure, Function, and Bioinformatics, Dec. 6, doi: 10.1002/prot.25636. [Epub ahead of print]. PMID: 30520161.
- Doyle JW, Glass KC, Racz M, Teng J. (2018) Student-Directed Interactive Animation for Learning Cytochrome P450-Mediated Drug Metabolism. Currents in Pharmacy Teaching and Learning, Dec 10(12):1565-1573. PMID: 30527821.
- Lloyd JT, Glass KC. (2018) Biological function and histone recognition of family IV bromodomain-containing proteins. Journal of Cellular Physiology, Mar;233(3):1877-1886. doi: 10.1002/jcp.26010. Epub 2017 Jun 13. PMID: 28500727.
- Jin K, Pandey NB, Popel AS. Simultaneous blockade of IL-6 and CCL5 signalling for synergistic inhibition of triple-negative breast cancer growth and metastasis. Breast Cancer Research 2018 Jun 14;20(1):54. (corresponding author).
- Norton KA, Jin K, Popel AS. Modeling triple-negative breast cancer heterogeneity: Effects of stromal macrophages, fibroblasts and tumor vasculature. Journal of Theoretical Biology 2018 Sep 7;452:56-68.
- Johng D, Torga G, Ewing CM, Jin K, Norris JD, McDonnell DP, Isaacs WB. HOXB13 interaction with MEIS1 modifies proliferation and gene expression in prostate cancer. Prostate 2018 Dec 17. doi: 10.1002/pros.23747. [Epub ahead of print].
- Malone MS, Smrekar K, Dnilova L, Considine M, Fertig E, Park S, Blakely B, Walter A, Nasta N, Park J, Jin K, Popel A. Cytokines secreted by stromal cells in TNBC microenvironment as potential targets for cancer therapy: experimental and bioinformatics predictions. Molecular Cancer Research 2018. (corresponding author, in review).
- Mall I, Musteata FM. Transdermal Sampling of Vitamin D3 and 25-Hydroxyvitamin D3. Bioanalysis, 11(2), Epub ahead of print , DOI 10.4155/bio-2018-0138, 2018 (corresponding author).
- Shah MB, Zhang Q, Halpert JR. Crystal Structure of CYP2B6 in Complex with an Efavirenz Analog. International Journal of Molecular Sciences. 2018. 19: 1025 (Corresponding Author).
Stanley Stevens
- Kriss CL, Gregory-Lott E, Storey AJ, Tackett AJ, Wahls WP, Stevens Jr. SM. In vivo metabolic tracing demonstrates the site-specific contribution of hepatic ethanol metabolism to histone acetylation. Alcoholism: Clinical and Experimental Research, 42(10):1909-1923 (2018).
- Rockfield J, Guergues J, Rehman N, Smith A, Bauckman KA, Stevens Jr. SM, Nanjundan M. Proteomic Profiling of Iron-Treated Serous Ovarian Cancer Cells Identifies AKT Activation, which Upregulates the CLEAR network. Proteomics, 18(23):e1800244 (2018).
- Pruyn S, Frey F, Brodeur M, Baker B, Long H, Graichen C, Zheng H, Dailey M. Quality Assessment of Expired Naloxone Products from First-Responders’ Supplies. Journal of Prehospital Emergency Medicine, E-published on December 30:1-7 (co-corresponding author).
Conferences and Presentations
- Krapah O,* Balaz S. Interaction of Amino Side Chains with the Surrogates of the Phospholipid Bilayer. ACPHS Student Summer Research Award Presentation, Albany NY, October 27, 2018 (Poster presenter: Opoku Krapah) *Recipient of an ACPHS Summer Student Research Award.
Yana Cen
- Rymarchyk S, Kisaka S, Urman L, Ayres R, Cen Y. Allosteric Activation of Human SIRT6. 8th Annual ACPHS Research Forum, Albany NY, January 2018 (Poster presentation).
- Tran A, Shek R, Yokose R, Wood M, French J, Cen Y. Identification and Characterization of Nucleobase Transporters. 8th Annual ACPHS Research Forum, Albany NY, January 2018 (Poster presentation).
- Zheng S, Cen Y. Synthesis of Cyclooctyne Containing Probes for Labeling Sirtuins. 8th Annual ACPHS Research Forum, Albany NY, January 2018 (Poster presentation).
- Cen Y. Novel Activity-Based Chemical Probes for Human Sirtuins. Spring 2018 ACS National Meeting, Early Career Investigators in Biological Chemistry session, New Orleans LA, March 2018 (Oral presentation).
- Cen Y. Sirtuin and NAD+: It Takes Two to Tango! Saint Michael’s College, Colchester VT, April 2018 (Invited talk).
- Tran A, Yokose R, Cen Y. Chemo-enzymatic Synthesis of Isotopically Labeled Nicotinamide Riboside. Gordon Research Conference on Enzymes, Coenzymes and Metabolic Pathways, Waterville Valley NH, July 2018 (Poster presentation).
- Cen Y, ElMageed Z, Fandy T. The impact of DNA hypomethylating agents on the activity of nuclear sirtuins, 2018 ACCP Annual Meeting, Bethesda MD, September 2018 (Poster presentation).
Karen C. Glass
- Glass KC. A link between ATAD2 bromodomain disulfide bridge formation and cancer progression? ACPHS Annual Research Forum, Albany NY, January 27, 2018 (Invited talk).
- Lloyd JT, Gay JC, Eckenroth BE, Tonelli M, Cornilescu G, Nguyen P, Carlson S, Markley JL, Glass KC. Structural insights into the recognition of mono- and di-acetyllysine by the ATAD2B bromodomain. ACPHS Annual Research Forum, Albany NY, Jan 27, 2018 (Poster presenter: KC Glass).
- Lloyd JT, Gay JC, Eckenroth BE, Tonelli M, Cornilescu G, Nguyen P, Carlson S, Markley JL and Glass KC. Structural insights into the recognition of mono- and di-acetyllysine by the ATAD2B bromodomain. Keystone Symposia on Cancer Epigenetics: New Mechanisms, New Therapies, Breckenridge CO, February 12, 2018 (Poster presenter: KC Glass).
- Lloyd JT, Gay JC, Eckenroth BE, Tonelli M, Cornilescu G, Nguyen P, Carlson S, Markley JL and Glass KC. Structural insights into the recognition of mono- and di-acetyllysine by the ATAD2B bromodomain. UVM Clinical and Translational Research Symposium on Cancer Control in a Rural Environment, Burlington VT, April 20, 2018 (Poster presenter: KC Glass).
- Evans CM, Gay JC, Eckenroth BE, Carlson S, Lloyd JT, Glass KC. Disulfide bridge formation contributes to histone ligand recognition by the ATAD2 bromodomain. ACPHS Annual Research Forum, Albany NY, Jan 27, 2018 (Poster presenter: Chiara Evans).
- Evans CM, Gay JC, Eckenroth BE, Carlson S, Lloyd JT, Glass KC. Disulfide bridge formation contributes to histone ligand recognition by the ATAD2 bromodomain. Keystone Symposia on Cancer Epigenetics: New Mechanisms, New Therapies, Breckenridge CO, February 12, 2018 (Poster presenter: Chiara Evans).
- Evans CM, Gay JC, Eckenroth BE, Carlson S, Lloyd JT, Glass KC. Disulfide bridge formation contributes to histone ligand recognition by the ATAD2 bromodomain. ACPHS Annual Student Research Symposium, Albany NY, April 3, 2018 (Poster presenter: Chiara Evans).
- Evans CM, Gay JC, Carlson S, Glass KC. Recognition of acetylated histone ligands by the ATAD2 bromodomain. AAPS-NERDG 2018 Annual Meeting, Farmington CT, April 12, 2018 (Poster presenter: Chiara Evans) **Recipient of the 2018 AAPS-ACPHS Student Researcher Award.
- Signorelli S, Gerrard D, Glass KC, Frietze S. Genome-Wide Analysis of Bromodomain Histone Di-Acetyllysine Ligands. UVM Undergraduate Research Conference, Burlington VT, April 19, 2018 (Poster presenter: Sylvia Signorelli).
- Signorelli S, Gerrard D, Glass KC, Frietze S. Genome-Wide Analysis of Bromodomain Histone Di-Acetyllysine Ligands. UVM Clinical and Translational Research Symposium on Cancer Control in a Rural Environment, Burlington VT, April 20, 2018 (Poster presenter: Sylvia Signorelli).
- Signorelli S, Gerrard D, Glass KC, Frietze S. Genome-Wide Analysis of Bromodomain Histone Di-Acetyllysine Ligands. ASBMB Annual Meeting, San Diego CA, April 21-25, 2018 (Poster presenter: Sylvia Signorelli).
- Evans CM, Gay JC, Eckenroth BE, Carlson S, Lloyd JT, Glass KC. Disulfide bridge formation contributes to histone ligand recognition by the ATAD2 bromodomain. ASBMB Annual Meeting, San Diego CA, April 21-25, 2018 (Poster presenter: Chiara Evans) **Recipient of an ASBMB 2018 Graduate/Postdoctoral Travel Award, $1000.
- Allen B, Olmstead F, Evans CM, Glass KC. Characterization of the Histone Ligands of the Plasmodium falciparum BDP1 Bromodomain. ACPHS Student Summer Research Award Presentation, Albany NY, October 27, 2018 (Poster presenter: Brittany Allen) **Recipient of an ACPHS Summer Student Research Award.
- Jin K. Crosstalk between Stromal Components and Endocrine Resistant Breast Cancer via Secreted Factors Enhances Tumor Growth and Metastasis. AACR Annual Meeting, Chicago IL, April 14-18, 2018.
- Jin K. Crosstalk between Stromal Components and Endocrine Resistant Breast Cancer via Secreted Factors Enhances Tumor Growth and Metastasis. SUNY Albany, CRC Research Seminar (invited talk).
- Jin K. Crosstalk between Stromal Components and Endocrine Resistant Breast Cancer via Secreted Factors Enhances Tumor Growth and Metastasis. 8th Annual Research Forum, Albany College of Pharmacy and Health Sciences, Albany NY, January 27, 2018 (invited talk).
- Mall I, Zheng H, Musteata FM. Transdermal Sampling of Vitamin D3 and 25-Hydroxyvitamin D3. AAPS-NERDG, Farmington CT, April 2018.
- Shah MB. 16th Annual International Conference 2018 - "The Road from Nano-medicine to Precision Medicine", Albany NY, September 17, 2018 (invited talk).
- Shah MB. Structural Determinants of Substrate Selectivity in Human Cytochromes P450 2C9 and 2C18. Experimental Biology 2018, San Diego CA, April 21-25 (poster presentation).
- Shah MB. Structural and Computational Insights into Single Nucleotide Polymorphisms in Cytochrome P450 2C9. 8th Annual ACPHS Research Forum, Albany NY, January 2018 (poster presentation).
- Garrison GD, Bidell M, Cabral K, Silvestro L, Boire A, Strang AF. Interdisciplinary Formative Assessments to Foster Student Learning in the Dual-Campus Large Classroom Setting (School Poster). AACP Annual Meeting, Boston MA, July 21-23, 2018. American Journal of Pharmaceutical Education 2018; 82 (5) Article 7160.
Stanley M. Stevens, Jr.
- Guergues J, Rath M, Pinho JP, Nguyen TG, Peris J, McLaughlin JP, MacFdyen K, Zhang P, Liu B, Stevens Jr. SM. Super-SILAC Analysis Reveals Sex Differences in Alcohol-Induced Microglial Activation: Potential Link to Anxiety Development After Chronic Alcohol Exposure in Mice. 66th ASMS Conference on Mass Spectrometry and Allied Topics, San Diego CA, 2018.
- Kriss C, Gregory-Lott E, Storey AJ, Stevens Jr. SM. In Vivo Metabolic Tracing Reveals Site-Specific Contribution of Hepatic Ethanol Metabolism to Histone Acetylation. 66th ASMS Conference on Mass Spectrometry and Allied Topics, San Diego CA, 2018.
- Stevens Jr. SM. Applications of Stable Isotope Labeling in MS, ASMS Conference, San Diego CA, 2018 (session chair).
- Frey J, Pruyn S, Brodeur M, Baker B, Graichen C, Dailey M, Zheng H. Quality Assessment of Expired Naloxone Products from First-Responders’ Supplies. ACPHS Annual Research Forum, Albany NY, January 2018.
- Frey J, Pruyn S, Brodeur M, Baker B, Graichen C, Dailey M, Zheng H. Quality Assessment of Expired Naloxone Products from First-Responders’ Supplies. AAPS Northeast Regional Annual Meeting, Farmington CT, April 12, 2018.
- Frey J, Pruyn S, Brodeur M, Baker B, Graichen C, Dailey M, Zheng H. Quality Assessment of Expired Naloxone Products from First-Responders’ Supplies. AACP Annual Meeting, Boston MA, July 22, 2018.
- Frey J, Pruyn S, Brodeur M, Baker B, Graichen C, Dailey M, Zheng H. Quality Assessment of Expired Naloxone Products from First-Responders’ Supplies. Chemistry and Pharmacology of Drug Abuse, Boston MA, August 2, 2018.
- Thurston AB, Zheng HA. Cannabinoid Receptor Expression on Human Embryotic Kidney Cells (HEK-293) and the Factors that Influence them. Chemistry and Pharmacology of Drug Abuse, Boston MA, August 2, 2018.
Grants
Karen C. Glass
Role: Co-Principal Investigator (Co-PI: Seth Frietze, University of Vermont)
Project Title: Deciphering the molecular mechanisms of histone code recognition by ATAD2/B
Grantor: National Institutes of Health, National Institute of General Medical Sciences
Grant Number: 1R01GM129338-01
Amount: $1,987,375
Term: 9/19/2018 – 8/31/2022
Marcel Musteata
Role: Co-Principal Investigator: Marcel Musteata (Co-PI: Michael Kane, ACPHS)
Project Title: Simultaneous Determination of Free, Total, and Normalized Concentrations of Bioactive Compounds
Grantor: National Institutes of Health, National Institute of General Medical Sciences
Grant Number: 1R15GM126510-01
Amount: $480,000
Term: 2018-2021
Stanley M. Stevens, Jr.
Role: Principal Investigator
Project Title: The role of histone demethylase KDM5B in ethanol-induced microglial activation
Grantor: National Institute on Alcohol Abuse and Alcoholism
Grant Number: 5R01AA026082-03
Amount: $379,402
Term: 7/01/2019 - 6/30/2019
Role: Principal Investigator
Project Title: Role of methylation in ethanol-induced microglial activation
Grantor: National Institute on Alcohol Abuse and Alcoholism
Grant Number: 7R21AA025183-02
Amount: $278,000
Term: 5/01/2018 - 4/30/2019
Honors, Awards and Appointments
- Member of the Editorial Boards of Current Computer-Aided Drug Design (Bentham) and Chemical Papers (Springer).
- Peer reviewer of manuscripts for Journal of Medicinal Chemistry, Journal of Chemical Information and Modeling, and Environmental Science and Technology.
Yana Cen
- Researcher of the Year, Albany College of Pharmacy and Health Sciences (awarded Jan. 2018)
- Early Career Reviewer, NIH SBCA Study Section
Karen C. Glass
- Peer reviewer for Cell Death & Disease, Journal of Medicinal Chemistry, PLOS ONE, and the Journal of Cellular Physiology.
- Ad hoc reviewer for NIH Center for Scientific Review Molecular Genetics A study (MGA) section meeting. 9/24 to 9/25/2018.
- Preclinical Catalyst Program Reviewer, Breast Cancer Now (UK)
- Associate Editor for Bioanalysis
- Member, Editorial Board of Current Metabolomics
- Member, Editorial Board of EC Pharmacology and Toxicology
Stanley Stevens
- Ad Hoc reviewer for NIH, Neurotoxicity and Alcohol Study Section (Feb. 22-23, 2018)